Zoviraxlabiale Cream 2 grams 5%

€10.25
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Minsan
037868015
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WARNINGS
The drug should only be used for cold sores present on the mouth. It is not recommended for application on mucous membranes such as those of the mouth, eyes and should not be used in the treatment of genital herpes. Particular care should be taken to avoid accidental application into the eye. It is recommended that people with particularly severe forms of recurrent cold sores consult their doctor. The use of the product, especially if prolonged, can give rise to sensitization phenomena: if this happens, the treatment must be interrupted and consult the treating doctor. It is recommended that those suffering from cold sores avoid transmission of the virus especially when active lesions are present (for example by washing their hands before and after applying the cream, see Posology and method of administration). The use of the drug in immunocompromised patients is not recommended. It is recommended that such patients consult their physician regarding the treatment of any infections. The medicine contains propylene glycol. It can cause skin irritation. The cream contains cetostearyl alcohol. It can cause local skin reactions (for example contact dermatitis).
PHARMACOTHERAPEUTIC CATEGORY
Topical chemotherapy.
STORAGE
Store at a temperature not exceeding 25 degrees C; do not refrigerate.
CONTRAINDICATIONS / SECONDARY EFFECT
Hypersensitivity 'to the active substance, to valaciclovir, or to any of the excipients; children under the age of 12.
NAME
ZOVIRAXLABIALE 5% CREAM
EXCIPIENTS
Poloxamer 407, cetostearyl alcohol, sodium lauryl sulfate, white vaseline, liquid paraffin, arlacel 165, dimethicone 20, propylene glycol, purified water.
SIDE EFFECTS
The undesirable effects reported for the medicinal product are listed according to the following frequency of occurrence convention: very common (> = 1/10), common (> = 1/100 and <1/10), uncommon (> = 1 / 1000 and <1/100), rare (> = 1/10000 and <1/1000), very rare (<1/10000), not known. Skin and subcutaneous tissue disorders. Uncommon: transient burning or stinging after application of the medicinal product, moderate dryness or peeling of the skin, itching; rare: erythema, contact dermatitis following application. Where sensitivity tests were conducted, it was shown that the substances that gave phenomena of reactivity were the components of the base cream rather than acyclovir. Disorders of the immune system. Very rare: immediate hypersensitivity including angioedema and urticaria.
PREGNANCY AND BREASTFEEDING
There are no data on the effects of aciclovir in oral or iv formulation for infusion on fertility in women. In a study of 20 male patients with normal sperm counts, acyclovir administered orally at doses up to 1 gram per day for up to 6 months was not shown to have an effect on sperm count, morphology and motility in humans. The use of the medicinal product should only be considered if the potential benefits outweigh the possibility of unknown risks. However, the systemic exposure to aciclovir following topical application of aciclovir cream is very low. A registry of post-marketing use of aciclovir in pregnancy provided data on pregnancy outcomes in women exposed to the various aciclovir formulations. These observations did not show an increase in the number of birth defects among subjects exposed to aciclovir compared to the general population and all birth defects found did not show any particularities or common characteristics that would suggest a single cause. Systemic exposure to aciclovir following topical application of aciclovir cream is very low. Although some data indicate that aciclovir passes into breast milk following systemic administration, the dose that an infant takes following use of the medicinal product in the mother should be insignificant. During pregnancy and lactation the product should be used only after medical consultation and having evaluated the risk / benefit ratio in the individual case.
INDICATIONS
Treatment of herpes simplex virus infections of the lips (recurrent herpes labialis) in adults and adolescents (over 12 years of age).
INTERACTIONS
No clinically significant interactions have been identified.
DOSAGE
Topical use. Adults and adolescents over 12 years of age: the drug must be applied 5 times a day at intervals of about 4 hours, omitting the night application. The medicine should be applied as early as possible, preferably during the earliest stages (prodrome or erythema). However, treatment can also be initiated in the later stages (papules or vesicles). Treatment should continue for at least 4 days. If there is no healing, treatment can continue for up to 10 days. Patients should wash their hands before and after applying the cream and avoid unnecessarily rubbing the lesions or touching them with a towel in order to avoid worsening or transmission of the infection. Children younger than 12 years: the safety and efficacy of the product have not been studied in patients younger than 12 years. Patients with renal or hepatic insufficiency: aciclovir is eliminated primarily via the kidney, but the systemic absorption of aciclovir after topical application is negligible. Consequently, no dose modification is required in patients with renal or hepatic insufficiency.
ACTIVE PRINCIPLES
Acyclovir.

037868015
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Zoviraxlabiale Cream 2...

€10.25