Neoborocillin Cough 20 Orosoluble Tablets

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027081049
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WARNINGS
In case of an irritating cough with significant mucus production (e.g. in patients with diseases such as bronchiectasis and cystic fibrosis) or in patients with neurological diseases associated with a marked reduction in the cough reflex (such as stroke, Parkinson's disease and dementia ), treatment with the drug as a cough suppressant should be administered with particular caution and only after careful risk-benefit assessment. There is limited information on the use of dextromethorphan in patients with impaired hepatic or renal function. Therefore, the medicinal product should be administered with caution in such patients, especially in patients with severe impairment. Due to the potential release of histamine, the use of the product in mastocytosis should be avoided.A chronic cough can be an early symptom of asthma and therefore the drug is not indicated for the suppression of chronic cough, particularly in children. . The medicine should be used with caution in patients taking serotonergic drugs (other than MAO inhibitor drugs), such as selective serotonin reuptake inhibitors (SSRIs) (e.g. fluoxetine, paroxetine) or tricyclic antidepressant drugs. The use, especially if prolonged, of products for topical use can give rise to sensitization phenomena. In this case it is necessary to interrupt the treatment and consult the doctor in order to establish any suitable therapy. The product contains sugar, which must be taken into account in case of diabetes or low-calorie diets. The product contains aspartame, a source of phenylalanine. Alcohol intake is not recommended during therapy. Dextromethorphan can 'give a modest addiction. Following prolonged use (e.g. exceeding the recommended treatment period), patients may develop tolerance to the drug, as well as mental and physical dependence. Patients with a tendency to abuse or dependence should take the drug for short periods. Cases of dextromethorphan abuse have been reported, predominantly in adolescents.
PHARMACOTHERAPEUTIC CATEGORY
Antitussives, excluding associations with expectorants.
STORAGE
Store below 30 degrees C.
CONTRAINDICATIONS / SECONDARY EFFECT
Hypersensitivity 'to the active ingredients or to any of the excipients; bronchial asthma, COPD, pneumonia, respiratory distress, respiratory depression, cardiovascular disease, hypertension, hyperthyroidism, diabetes, glaucoma, prostatic hypertrophy, stenosis of the gastrointestinal and urogenital tract, epilepsy, severe liver disease; do not administer to children younger 'less than 12 years; do not use at the same time or in the two weeks following treatment with MAO inhibitor antidepressant drugs; since the product contains aspartame, a source of phenylalanine, it is contraindicated in subjects suffering from phenylketonuria; it also contains sugar, therefore it is contraindicated in case of hereditary intolerance to fructose, in the glucose / galactose malabsorption syndrome and in sucrase / isomaltase deficiency; pregnancy, especially in the first trimester, lactation.
NAME
NEO COUGH BOROCILLIN 10 MG + 1.2 MG TABLETS
EXCIPIENTS
Aroma freshflavor, ammonium glycyrrhizinate, magnesium stearate, aspartame (E 951), compressible sugar.
SIDE EFFECTS
Insufficient data are available to establish the frequency of the listed effects. Immune system disorders: hypersensitivity reactions' (including anaphylactic reaction, angioedema, urticaria, pruritus, rash and erythema) Metabolism and nutrition disorders, decreased appetite. Psychiatric disorders: hallucinations, abuse and dependence on dextromethorphan. Nervous system disorders: drowsiness. Ear and labyrinth disorders: dizziness. Respiratory, thoracic and mediastinal disorders: respiratory depression. Gastrointestinal disorders: nausea, vomiting, gastrointestinal disturbances. General Disorders and Administration Site Conditions: Fatigue. The reporting of suspected adverse reactions that occur after the authorization of the drug is important, as it allows continuous monitoring of the benefit / risk ratio of the drug.
PREGNANCY AND BREASTFEEDING
The medicine should not be used during the first three months of pregnancy; in the following months the drug must be administered only in case of actual need. Since excretion of the drug in breast milk is not known and a respiratory depressive effect on the newborn cannot be excluded, the drug is contraindicated during breastfeeding.
INDICATIONS
Sedative of cough and antiseptic of the oropharyngeal cavity.
INTERACTIONS
Dextromethorphan has weak serotonergic properties. Dextromethorphan can therefore lead to an increased risk of serotonin toxicity (serotonin syndrome), especially when taken together with other serotonergic agents, such as MAO inhibitors or SSRIs or tricyclic antidepressants. Especially pre-treatment or concomitant treatment with drugs that impair serotonin metabolism, such as antidepressant drugs of the MAO inhibitor type, may induce the development of a serotonin syndrome with the following characteristic symptoms: neuromuscular hyperactivity (e.g. tremor , clonic spasm, myoclonus, increased reflex response and rigidity of pyramidal origin), hyperactivity of the autonomic nervous system (e.g. diaphoresis, fever, tachycardia, tachypnea, mydriasis) and altered mental status (e.g. agitation, excitement, confusion). Co-administration of drugs with an inhibitory effect on the central nervous system such as hypnotics, sedatives or anxiolytics, or the intake of alcohol, can lead to additive effects. Coadministration of drugs, such as amiodarone, quinidine, fluoxetine, haloperidol, paroxetine, propafenone, thioridazine, cimetidine, ritonavir, berberine, bupropion, cinacalcet, flecainide and terbinafine, which inhibit the liver, and therefore cytochrome P450-2 enzymatic system, the metabolism of dextromethorphan may lead to an increase in the plasma concentration of dextromethorphan. Even if they are no longer taken at the moment, these effects may occur if these medicines have been taken recently. If dextromethorphan is used in combination with mucolytics in patients with pre-existing diseases of the respiratory tract, such as cystic fibrosis and bronchiectasis, suffering from mucus hypersecretion, the reduced cough reflex can lead to a (severe) accumulation of mucus.
DOSAGE
Adults and children over 12 years: slowly dissolve one tablet in the mouth every 2-3 hours, up to a maximum of 8 tablets per day. Do not exceed the recommended doses.
ACTIVE PRINCIPLES
Dextromethorphan hydrobromide; 2,4-Dichlorobenzyl alcohol.
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Neoborocillin Cough 20...

€10.60